Search on: CORE BINDING FACTOR ALPHA 2 PROTEIN 
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Descriptor English:   Core Binding Factor Alpha 2 Subunit 
Descriptor Spanish:   Subunidad alfa 2 del Factor de Unión al Sitio Principal 
Descriptor Portuguese:   Subunidade alfa 2 de Fator de Ligação ao Core 
Synonyms English:   AML1A Protein
AML1B Protein
AML1C Protein
AML1D Protein
Acute Myeloid Leukemia 1 Protein
Acute Myeloid Leukemia 1A Protein
Acute Myeloid Leukemia 1B Protein
Acute Myeloid Leukemia 1C Protein
Acute Myeloid Leukemia 1D Protein
Core-Binding Factor Alpha 2 Protein
Pebp2a2 Protein
Runt-Related Transcription Factor 1
Runx1 Protein
Core Binding Factor Alpha 2 Protein
Runt Related Transcription Factor 1  
Tree Number:   D12.776.930.155.200.200
Definition English:   A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain. Runx1 is frequently mutated in human LEUKEMIAS. 
Indexing Annotation English:   see SCR for organism-specific terms
History Note English:   2006(1993) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   51177 
Unique Identifier:   D050676 

Occurrence in VHL:
 

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